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IFT74 抗体 (AA 1-375) (Cy3)

The 兔 多克隆 anti-IFT74 antibody is suitable to detect IFT74 in samples from 人, 大鼠, 小鼠 和 猴. It has been validated for FACS.
产品编号 ABIN8003136
发货至: 中国
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Quick Overview for IFT74 抗体 (AA 1-375) (Cy3) (ABIN8003136)

抗原

See all IFT74 抗体
IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

适用

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人, 大鼠, 小鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This IFT74 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 15
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    AA 1-375

    原理

    Anti-IFT74 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))

    别名

    IFT74

    背景

    Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

    Gene Full Name: intraflagellar transport 74

    基因ID

    80173

    UniProt

    Q96LB3

    途径

    Hedgehog Signaling, Chromatin Binding
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