IFT74 抗体 (AA 1-375) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for IFT74 抗体 (AA 1-375) (Cy3) (ABIN8003136)
抗原
See all IFT74 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-375
-
原理
- Anti-IFT74 Antibody Cy3 Conjugated
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
-
别名
- IFT74
-
背景
-
Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
Gene Full Name: intraflagellar transport 74
-
基因ID
- 80173
-
UniProt
- Q96LB3
-
途径
- Hedgehog Signaling, Chromatin Binding
抗原
-