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IRAK3 抗体 (C-Term)

The 兔 多克隆 anti-IRAK3 antibody (ABIN8002969) specifically detects IRAK3 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN8002969
发货至: 中国
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Quick Overview for IRAK3 抗体 (C-Term) (ABIN8002969)

抗原

See all IRAK3 抗体
IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

适用

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宿主

  • 89
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克隆类型

  • 71
  • 26
多克隆

标记

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This IRAK3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 15
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    C-Term

    原理

    Anti-IRAKM/IRAK3 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-IRAKM/IRAK3 Antibody-1. Tested in WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human IRAKM.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

    别名

    IRAK3

    背景

    Background: Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.

    Gene Full Name: interleukin 1 receptor associated kinase 3

    Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.

    分子量

    53 kDa

    基因ID

    11213

    UniProt

    Q9Y616

    途径

    TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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