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IL7R 抗体 (AA 33-433) (Fluoro550)

The 兔 多克隆 anti-IL7R antibody is suitable to detect IL7R in samples from 人. It has been validated for FACS.
产品编号 ABIN8002863
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for IL7R 抗体 (AA 33-433) (Fluoro550) (ABIN8002863)

抗原

See all IL7R 抗体
IL7R (Interleukin 7 Receptor (IL7R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL7R antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
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    AA 33-433

    原理

    Anti-CD127/IL7R Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human IL7R shares 63.1% amino acid (aa) sequence identity with mouse IL7R.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD127/IL7R recombinant protein (Position: A33-Q433). Human IL7R shares 63.1% amino acid (aa) sequence identity with mouse IL7R.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IL7R (Interleukin 7 Receptor (IL7R))

    别名

    IL7R

    背景

    Background: The interleukin-7 receptor, also known as IL7R alpha, is a protein found on the surface of cells. It is mapped to 5p13. Interleukin-7 receptor has been shown to play a critical role in the development of immune cells called lymphocytes - specifically in a process known as V(D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. Knockout studies in mice suggest that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. Functional defects in this protein may be associated with the pathogenesis of severe combined immunodeficiency (SCID).

    Gene Full Name: interleukin 7 receptor

    基因ID

    3575

    UniProt

    P16871

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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