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IL4 Receptor 抗体 (AA 26-719) (HRP)

The 兔 多克隆 anti-IL4 Receptor antibody is suitable to detect IL4 Receptor in samples from 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN8002701
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL4 Receptor 抗体 (AA 26-719) (HRP) (ABIN8002701)

抗原

See all IL4 Receptor (IL4R) 抗体
IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

适用

  • 77
  • 52
  • 35
  • 2
小鼠, 大鼠

宿主

  • 92
  • 16
  • 10
  • 2
  • 2

克隆类型

  • 95
  • 23
  • 2
多克隆

标记

  • 61
  • 10
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL4 Receptor antibody is conjugated to HRP

应用范围

  • 80
  • 39
  • 32
  • 20
  • 14
  • 13
  • 11
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 15
    • 12
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-719

    原理

    Anti-IL4R Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat IL4R recombinant protein (Position: I26-E719).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

    别名

    Il4r

    背景

    Background: IL4R (INTERLEUKIN 4 RECEPTOR) is a human gene that encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. The IL4R gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines. IL4 plays a major role in immunoglobulin E (IgE) production. Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor. IL4 interacts with IL4R with high affinity, leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines, to create a type I receptor, or with IL13RA1 to form a type II receptor.The IL4R gene contains 12 exons and IL4R is a complex of at least 2 components, one of which is a novel affinity converting subunit that is critical for cellular signal transduction. See also IL13RA1 and IL13RA2.

    Gene Full Name: interleukin 4 receptor

    基因ID

    25084

    UniProt

    Q63257

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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