IL4 Receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for IL4 Receptor 抗体 (ABIN7215426)
抗原
See all IL4 Receptor (IL4R) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-IL-4Rα Polyclonal Antibody
-
特异性
- IL-4Rα Polyclonal Antibody detects endogenous levels of IL-4Rα protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from human IL-4Ralpha around the non-phosphorylation site of Y497
-
亚型
- IgG
-
-
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibody
IL4R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-233) antibodyIL4R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 201-300) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B12B12 unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 1-227) antibodyIL4R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (N-Term) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (Ser540) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 677-691), (C-Term) antibodyIL4R 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB48074 unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
-
别名
- IL-4Ralpha
-
背景
- IL4R, IL4RA, 582J2.1, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD antigen CD124IL4R encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. Interleukin-4 receptor subunit alpha also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
-
分子量
- 90kD
-
基因ID
- 3566
-
UniProt
- P24394
-
途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
-
