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IL21 Receptor 抗体 (Middle Region) (HRP)

The HRP-conjugated 兔 多克隆 anti-IL21 Receptor antibody (ABIN8002327) specifically detects IL21 Receptor in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN8002327
发货至: 中国
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Quick Overview for IL21 Receptor 抗体 (Middle Region) (HRP) (ABIN8002327)

抗原

See all IL21 Receptor (IL21R) 抗体
IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL21 Receptor antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    原理

    Anti-IL21R Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human IL21R shares 78.6% amino acid (aa) sequence identity with mouse IL21R.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human IL21R. Human IL21R shares 78.6% amino acid (aa) sequence identity with mouse IL21R.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

    别名

    IL21R

    背景

    Background: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

    Gene Full Name: interleukin 21 receptor

    基因ID

    50615

    UniProt

    Q9HBE5

    途径

    JAK/STAT Signaling
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