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IL21 Receptor 抗体 (AA 20-232)

IL21R 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 8H10G4D12 unconjugated
产品编号 ABIN7193230
发货至: 中国
  • 抗原 See all IL21 Receptor (IL21R) 抗体
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    抗原表位
    • 15
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-232
    适用
    • 30
    • 29
    • 7
    • 2
    宿主
    • 42
    • 3
    • 2
    • 2
    小鼠
    克隆类型
    • 44
    • 4
    • 1
    单克隆
    标记
    • 28
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL21 Receptor antibody is un-conjugated
    应用范围
    • 35
    • 19
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CD360 (AA: extra 20-232) expressed in E. coli.
    克隆位点
    8H10G4D12
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    别名
    CD360 (IL21R 产品)
    别名
    IL21R antibody, il-21ra.a antibody, CD360 antibody, NILR antibody, interleukin 21 receptor antibody, interleukin 21 receptor, tandem duplicate 1 antibody, IL21R antibody, il21r.1 antibody, Il21r antibody
    背景

    Description: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

    Aliases: IL21R, NILR, IMD56

    分子量
    59.1 kDa
    基因ID
    50615
    途径
    JAK/STAT Signaling
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