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IL21 Receptor 抗体 (Middle Region) (Cy3)

This 兔 多克隆 antibody specifically detects IL21 Receptor in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8002322
发货至: 中国
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Quick Overview for IL21 Receptor 抗体 (Middle Region) (Cy3) (ABIN8002322)

抗原

See all IL21 Receptor (IL21R) 抗体
IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL21 Receptor antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 15
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    Middle Region

    原理

    Anti-IL21R Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human IL21R shares 78.6% amino acid (aa) sequence identity with mouse IL21R.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human IL21R. Human IL21R shares 78.6% amino acid (aa) sequence identity with mouse IL21R.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

    别名

    IL21R

    背景

    Background: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

    Gene Full Name: interleukin 21 receptor

    基因ID

    50615

    UniProt

    Q9HBE5

    途径

    JAK/STAT Signaling
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