IL2 Receptor beta 抗体 (AA 268-551) (Fluoro594)
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北京 101111
Quick Overview for IL2 Receptor beta 抗体 (AA 268-551) (Fluoro594) (ABIN8002270)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 268-551
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原理
- Anti-IL2 Receptor beta/p75/IL2RB Antibody Fluoro594 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IL2 Receptor beta/p75/IL2RB recombinant protein (Position: R268-V551).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- IL2RB
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背景
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Background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Gene Full Name: interleukin 2 receptor subunit beta
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基因ID
- 3560
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UniProt
- P14784
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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