IRF3 抗体 (AA 1-419) (PE)
Our Local Distributor
北京 101111
Quick Overview for IRF3 抗体 (AA 1-419) (PE) (ABIN8001206)
抗原
See all IRF3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-419
-
原理
- Anti-IRF3 Antibody (monoclonal, 7B10) PE Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived mouse IRF3 recombinant protein (Position: M1-I419).
-
亚型
- IgG2b
-
-
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibodyIRF3 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibodyIRF3 适用: 人, 小鼠, 大鼠, 猴, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 5-422) antibodyIRF3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibodyIRF3 适用: 人 WB, IHC, FACS, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibodyIRF3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibodyIRF3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4C3 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-419) antibodyIRF3 适用: 小鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
别名
- Irf3
-
背景
-
Background: IRF3 (interferon regulatory factor 3) is a member of the interferon regulatory transcription factor (IRF) family. The IRF3 gene is mapped on 19q13.33. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. IRF3 plays an important role in the innate immune system's response to viral infection. Aggregated MAVS have been found to activate IRF3 dimerization. Although IRF3 increased transcriptional activity from an ISRE-containing promoter, expression of IRF3 as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase (CAT) < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>reporter gene containing repeats of the Gal4-binding sites. Translocation of IRF3 was accompanied by an increase in serine and threonine phosphorylation. The transcriptional activators CREBBP and EP300 coimmunoprecipitated with IRF3 only subsequent to viral infection, and the authors stated that these are also subunits of DRAF1.
Gene Full Name: interferon regulatory factor 3
-
基因ID
- 54131
-
UniProt
- P70671
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
抗原
-
