ITGB3BP 抗体 (AA 1-177) (HRP)
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北京 101111
Quick Overview for ITGB3BP 抗体 (AA 1-177) (HRP) (ABIN8000567)
抗原
See all ITGB3BP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-177
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原理
- Anti-Centromere protein R/ITGB3BP Antibody HRP Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human ITGB3BP shares 94.4%,59.8% amino acid (aa) sequence identity with mouse,rat ITGB3BP,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Centromere protein R/ITGB3BP recombinant protein (Position: M1-N177). Human ITGB3BP shares 94.4% and 59.8% amino acid (aa) sequence identity with mouse and rat ITGB3BP, respectively.
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亚型
- IgG
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anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-100) antibody
ITGB3BP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) antibodyITGB3BP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (Internal Region) antibodyITGB3BP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 36-85) antibodyITGB3BP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-111) antibodyITGB3BP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
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别名
- ITGB3BP
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背景
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Background: Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Gene Full Name: integrin subunit beta 3 binding protein
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基因ID
- 23421
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UniProt
- Q13352
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途径
- Neurotrophin Signaling Pathway
抗原
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