ITGB3BP 抗体 (AA 10-90)
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北京 101111
Quick Overview for ITGB3BP 抗体 (AA 10-90) (ABIN7227848)
抗原
See all ITGB3BP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Rabbit Anti-CENPR Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CENPR protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human CENPR protein at AA range: 10-90
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亚型
- IgG
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anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-100) antibody
ITGB3BP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) antibodyITGB3BP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (Internal Region) antibodyITGB3BP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 36-85) antibodyITGB3BP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-111) antibodyITGB3BP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
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别名
- CENPR
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背景
- Centromere protein R, CENP-R, Beta-3-endonexin, Integrin beta-3-binding protein, Nuclear receptor-interacting factor 3ITGB3BP (Integrin Subunit Beta 3 Binding Protein) encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. ITGB3BP also acts as a corepressor of NF-kappaB-dependent signaling. ITGB3BP induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. ITGB3BP is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
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分子量
- 19kD
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基因ID
- 23421
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UniProt
- Q13352
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途径
- Neurotrophin Signaling Pathway
抗原
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