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ITGB3BP 抗体 (AA 1-177) (FITC)

The FITC-conjugated 兔 多克隆 anti-ITGB3BP antibody (ABIN8000566) specifically detects ITGB3BP in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8000566
发货至: 中国
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Quick Overview for ITGB3BP 抗体 (AA 1-177) (FITC) (ABIN8000566)

抗原

See all ITGB3BP 抗体
ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

适用

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宿主

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克隆类型

  • 34
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多克隆

标记

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This ITGB3BP antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-177

    原理

    Anti-Centromere protein R/ITGB3BP Antibody FITC Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human ITGB3BP shares 94.4%,59.8% amino acid (aa) sequence identity with mouse,rat ITGB3BP,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Centromere protein R/ITGB3BP recombinant protein (Position: M1-N177). Human ITGB3BP shares 94.4% and 59.8% amino acid (aa) sequence identity with mouse and rat ITGB3BP, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

    别名

    ITGB3BP

    背景

    Background: Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

    Gene Full Name: integrin subunit beta 3 binding protein

    基因ID

    23421

    UniProt

    Q13352

    途径

    Neurotrophin Signaling Pathway
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