IDE 抗体 (AA 485-756) (HRP)
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北京 101111
Quick Overview for IDE 抗体 (AA 485-756) (HRP) (ABIN7999939)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 485-756
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原理
- Anti-Insulin degrading enzyme/IDE Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IDE recombinant protein (Position: F485-K756).
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亚型
- IgG
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anti-Insulin-Degrading Enzyme (IDE) (AA 491-590) antibody
IDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 753-973) antibodyIDE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 1-250) antibodyIDE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyKD Validated IDE 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6210 unconjugated Recombinant Antibody
anti-Insulin-Degrading Enzyme (IDE) (AA 485-756) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Insulin-Degrading Enzyme (IDE) (Internal Region) antibodyVerified IDE 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 920-1019) antibodyIDE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (N-Term) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- IDE
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背景
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Background: Insulin-degrading enzyme, also known as IDE, is an enzyme. This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Full Name: insulin degrading enzyme
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基因ID
- 416
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UniProt
- P14735
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途径
- SARS-CoV-2 Protein Interactome
抗原
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