IKZF3 抗体 (AA 162-498)
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Quick Overview for IKZF3 抗体 (AA 162-498) (ABIN7999136)
抗原
See all IKZF3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 162-498
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原理
- Anti-IKZF3 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PARP3 shares 82.2% amino acid (aa) sequence identity with mouse,rat PARP3.
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产品特性
- Anti-IKZF3 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PARP3 recombinant protein (Position: Q162-Q498). Human PARP3 shares 82.2% amino acid (aa) sequence identity with mouse and rat PARP3.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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别名
- IKZF3
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背景
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Background: Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Gene Full Name: IKAROS family zinc finger 3
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分子量
- 70 kDa
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基因ID
- 22806
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UniProt
- Q9UKT9
抗原
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