HDAC8 抗体 (N-Term)
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北京 101111
Quick Overview for HDAC8 抗体 (N-Term) (ABIN7997870)
抗原
See all HDAC8 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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原理
- Anti-Histone deacetylase 8 HDAC8 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by two amino acids.
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产品特性
- Anti-Histone deacetylase 8 HDAC8 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC8, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Histone Deacetylase 8 (HDAC8) antibody
KO Validated HDAC8 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyKD Validated HDAC8 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2495 unconjugated Recombinant Antibody
anti-Histone Deacetylase 8 (HDAC8) (AA 1-100) antibodyHDAC8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (pSer39) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IF (cc), IHC (p) 宿主: 兔 Monoclonal 4C3 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (C-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (N-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, MouseWestern blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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别名
- HDAC8
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背景
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Background: HDAC8, Histone deacetylase 8, is an enzyme that in humans is encoded by the HDAC8 gene, and is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Sequence analysis predicted that the 377-amino acid HDAC8 protein contains the 9 conserved HDAC blocks that are presumably important for catalytic function. HDAC8 shares 54 % sequence similarity with HDAC1 and HDAC2 and 39 % similarity with HDAC3, making it a class I HDAC. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
Gene Full Name: histone deacetylase 8
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分子量
- 42 kDa
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基因ID
- 55869
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UniProt
- Q9BY41
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途径
- Cellular Glucan Metabolic Process
抗原
-
