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HMGB1 抗体 (C-Term) (Fluoro550)

The 小鼠 单克隆 anti-HMGB1 antibody is suitable to detect HMGB1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN7997566
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HMGB1 抗体 (C-Term) (Fluoro550) (ABIN7997566)

抗原

See all HMGB1 抗体
HMGB1 (High Mobility Group Box 1 (HMGB1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 169
  • 54
  • 2
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  • 2
  • 1
小鼠

克隆类型

  • 144
  • 88
单克隆

标记

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This HMGB1 antibody is conjugated to Fluoro550

应用范围

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  • 9
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  • 4
  • 2
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  • 1
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Flow Cytometry (FACS)

克隆位点

5H3
  • 抗原表位

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    C-Term

    原理

    Anti-HMGB1 Antibody (monoclonal, 5H3) Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HMGB1, identical to the related mouse and rat sequences.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    HMGB1 (High Mobility Group Box 1 (HMGB1))

    别名

    HMGB1

    背景

    Background: High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

    Gene Full Name: high mobility group box 1

    基因ID

    3146

    UniProt

    P09429

    途径

    p53 Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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