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HSP70 1A 抗体 (C-Term)

The 兔 多克隆 anti-HSP70 1A antibody (ABIN7996340) specifically detects HSP70 1A in WB, IHC 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7996340
发货至: 中国
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Quick Overview for HSP70 1A 抗体 (C-Term) (ABIN7996340)

抗原

See all HSP70 1A (HSPA1A) 抗体
HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 107
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多克隆

标记

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This HSP70 1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

质量等级

Carrier-free
  • 抗原表位

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    C-Term

    原理

    Anti-Hsp70/HSPA1A/HSPA1B Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by four amino acids,from the related rat sequence by three amino acids.

    产品特性

    Anti-Hsp70/HSPA1A/HSPA1B Antibody. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp70, different from the related mouse sequence by four amino acids and from the related rat sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat Immunocytochemistry , 0.5-1 μg/mL, Human, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.01 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

    别名

    HSPA1A

    背景

    Background: HSPA1 (heat shock 70kDa protein 1A) also known as HSP70-1, HSPA1A, HSP70-1A, HSP72 or HSP70I, is a protein that in humans is encoded by the HSPA1A gene. This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. The HSPA1A gene encodes a predicted 641-amino acid protein. The HSPA1 gene is mapped on 6p21.33. Shimizu et al. (1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2, which is found in the more common HSPA1A transcript. No protein was associated with expression of this short HSPA1A mRNA, possibly due to lack of a TATA box or loss of internal ribosome binding sites. Treatment with BGP-15, a pharmacologic inducer of Hsp72 that can protect against obesity-induced insulin resistance, improved muscular architecture, strength, and contractile function in severely affected diaphragm muscles in mdx dystrophic mice.

    Gene Full Name: heat shock protein family A (Hsp70) member 1A/1B

    Sequence Similarities: Belongs to the heat shock protein 70 family.

    分子量

    70 kDa

    基因ID

    3303, 3304

    UniProt

    P0DMV8

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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