我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

HSP70 1A 抗体 (C-Term)

Name: HSP70 1A 抗体 (C-Term)
SKU: ABIN3043849
Availability: OutOfStock

This 兔多克隆 antibody specifically detects HSP70 1A in WB, IHC, IF, ICC 和 FACS. It exhibits reactivity toward 人, 小鼠和大鼠. It has been mentioned in 13+ publications

Western blot analysis of Hsp70 using anti-Hsp70 antibody (ABIN3043849). (HSP70 1A 抗体 (C-Term))

IHC (p)

IHC

Western Blotting (WB) image for anti-Heat Shock 70kDa Protein 1A (HSPA1A) (C-Term) antibody (ABIN3043849) (HSP70 1A 抗体 (C-Term))

IHC analysis of Hsp70 using anti-Hsp70 antibody (ABIN3043849). (HSP70 1A 抗体 (C-Term))

IHC

Flow Cytometry analysis of Hela cells using anti-Hsp70 antibody (ABIN3043849). (HSP70 1A 抗体 (C-Term))

FACS

8 images

(13 references)

产品编号 ABIN3043849

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HSP70 1A 抗体 (C-Term) (ABIN3043849)

抗原

See all HSP70 1A (HSPA1A) 抗体

HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This HSP70 1A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Discover our top product HSPA1A Primary Antibody

抗原表位
38

14

8

6

6

5

4

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

原理

Anti-Hsp70/HSPA1A/HSPA1B Antibody

序列

KGKISEADKK KVLDKCQEVI SWLDANTLAE KDEFEHKR

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

different from the related mouse sequence by five amino acids,and from the related rat sequence by three amino acids.

产品特性

Anti-Hsp70/HSPA1A/HSPA1B Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp70, different from the related mouse sequence by five amino acids, and from the related rat sequence by three amino acids.

亚型

IgG
anti-Heat Shock 70kDa Protein 1A (HSPA1A) (Center) antibody
HSPA1A 适用: 人, 小鼠, 大鼠 WB, IP, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (AA 285-641) antibody
HSPA1A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (AA 1-641) antibody
HSPA1A 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) antibody
HSPA1A 适用: 人, 犬, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C6 unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (AA 500-600) antibody
HSPA1A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (AA 285-641) antibody
HSPA1A 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (C-Term) antibody
HSPA1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (C-Term) antibody
HSPA1A 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 3H5 unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) antibody
HSPA1A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB58828 unconjugated

anti-Heat Shock 70kDa Protein 1A (HSPA1A) (AA 1-641) antibody
HSPA1A 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 2# unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zeng, Xiao, Deng, Li: "Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 8985623, (2017) (PubMed).

Zhang, Tang, Li, Li, Zhang, Yan, Cui: "Effects of intracerebral hemorrhage and subsequent minimally invasive hematoma aspiration on expression of apoptosisrelated genes in rats." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 5371-8, (2016) (PubMed).

Chen, Wan, Huang, Wang, Liu, Wang: "Study on the immune response to recombinant Hsp70 protein from Megalobrama amblycephala." in: Immunobiology, Vol. 219, Issue 11, pp. 850-8, (2014) (PubMed).

Jing, Liu, Chen, Hu, Xiao, Ma: "Acute effect of copper and cadmium exposure on the expression of heat shock protein 70 in the Cyprinidae fish Tanichthys albonubes." in: Chemosphere, Vol. 91, Issue 8, pp. 1113-22, (2013) (PubMed).

Pu, Shi, Wang, Wang, Guo, Liu, Sun, Gao, Zhou: "Effects of minocycline on the expression of NGF and HSP70 and its neuroprotection role following intracerebral hemorrhage in rats." in: Journal of biomedical research, Vol. 25, Issue 4, pp. 292-8, (2013) (PubMed).

Chen, Zuo, Yang, Lu, Wang, Wang, Tu, Chen, Liu, Liu, Xiao: "Severe multiple organ injury in HSF1 knockout mice induced by lipopolysaccharide is associated with an increase in neutrophil infiltration and surface expression of adhesion molecules." in: Journal of leukocyte biology, Vol. 92, Issue 4, pp. 851-7, (2012) (PubMed).

Li, Roubeix, Wang, Shi, Liu, Baudouin, Chen: "Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye induced by an intelligently controlled environmental system." in: Molecular vision, Vol. 18, pp. 317-29, (2012) (PubMed).

Fan, Jiang, Yang, Liu, Song, Pan: "Effects of adrenergic agents on stress-induced brain microstructural and immunochemical changes in adult male Wistar rats." in: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, Vol. 193, Issue 5, pp. 418-24, (2011) (PubMed).

Xu, Luo, Wu, Chen, Xu, Gao, He, Geng, Xiao, Zhang, Chen, Li: "Immunohistological evaluation of skin responses after treatment using a fractional ultrapulse carbon dioxide laser on back skin." in: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], Vol. 37, Issue 8, pp. 1141-9, (2011) (PubMed).

Ouyang, Gao, Wang, Xie, Lei, Zhou, Liao, Zhong, Tang: "Thermoseed hyperthermia treatment of mammary orthotopic transplantation tumors in rats and impact on immune function." in: Oncology reports, Vol. 24, Issue 4, pp. 973-9, (2010) (PubMed).

Yi, Peng, Chang, Peng, Yan, Lin: "Effect of pre-moxibustion on apoptosis and proliferation of gastric mucosa cells." in: World journal of gastroenterology, Vol. 13, Issue 15, pp. 2174-8, (2007) (PubMed).

Wu, Cao, Gao, Chen, Wang, Zumbika, Qian: "Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 10, Issue 20, pp. 2944-8, (2004) (PubMed).

Gnatyshak, Loginskiĭ, Mazurok: "[Homo- and autotransplantation of bone marrow in radiation and chemotherapy of oncologic patients]." in: Vrachebnoe delo, Vol. 4, pp. 129-32, (1973) (PubMed).
抗原

HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

别名

HSPA1A

背景

Background: HSPA1 (heat shock 70 kDa protein 1A) also known as HSP70-1, HSPA1A, HSP70-1A, HSP72 or HSP70I, is a protein that in humans is encoded by the HSPA1A gene. This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. The HSPA1A gene encodes a predicted 641-amino acid protein. The HSPA1 gene is mapped on 6p21.33. Shimizu et al. (1999) found that peripheral blood mononuclear cells of 18 major depression patients expressed a short HSPA1A transcript that utilized exon 1 rather than exon 2, which is found in the more common HSPA1A transcript. No protein was associated with expression of this short HSPA1A mRNA, possibly due to lack of a TATA box or loss of internal ribosome binding sites. Treatment with BGP-15, a pharmacologic inducer of Hsp72 that can protect against obesity-induced insulin resistance, improved muscular architecture, strength, and contractile function in severely affected diaphragm muscles in mdx dystrophic mice.
Gene Full Name: Heat shock 70 kDa protein 1A
Sequence Similarities: Contains 1 HMG box DNA-binding domain.

分子量

70 kDa

基因ID

3303, 3304

UniProt

P0DMV8

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process