HSPE1 抗体 (C-Term) (Fluoro594)
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Quick Overview for HSPE1 抗体 (C-Term) (Fluoro594) (ABIN7996169)
抗原
See all HSPE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Cpn10/HSPE1 Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Cpn10, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
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别名
- HSPE1
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背景
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Background: HSPE1 (heat shock 10 kDa protein 1 (chaperonin 10)), also called CPN10, GROES, CHAPERONIN 10 HOMOLOG, cpn10 HOMOLOG or HSP10, is a protein that in humans is encoded by the HSPE1 gene. GroES is a heptameric ring of identical 10.4-kD subunits that binds to each end of GroEL to form a symmetric, functional heterodimer. The HSP10 gene consists of 4 exons. The HSPE1 gene is mapped to 2q33.1. The transcriptional activity of the promoter fragment in the HSP60 ion is approximately twice that in the HSP10 ion under normal growth conditions, upon heat shock, promoter activity in either ion increased by a factor of approximately 12. Mutational drifts performed in vitro with 4 different enzymes indicated the GroES overexpression doubled the number of accumulating mutations, and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with higher destabilizing effects.
Gene Full Name: heat shock protein family E (Hsp10) member 1
Sequence Similarities: Belongs to the heat shock protein 70 family.
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基因ID
- 3336
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UniProt
- P61604
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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