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HSPE1 抗体 (Internal Region)

HSPE1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262388
发货至: 中国
  • 抗原 See all HSPE1 抗体
    HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
    抗原表位
    • 23
    • 15
    • 11
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 104
    • 48
    • 41
    • 18
    • 18
    • 17
    • 17
    • 15
    • 15
    • 15
    • 15
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 120
    • 3
    • 2
    • 1
    克隆类型
    • 113
    • 13
    多克隆
    标记
    • 43
    • 17
    • 10
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HSPE1 antibody is un-conjugated
    应用范围
    • 89
    • 53
    • 49
    • 30
    • 26
    • 24
    • 19
    • 16
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    HSP10 Antibody detects endogenous levels of total HSP10.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Rabbit,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HSP10, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product HSPE1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
    别名
    HSPE1 (HSPE1 产品)
    别名
    CPN10 antibody, EPF antibody, GROES antibody, HSP10 antibody, groS antibody, Cpn10 antibody, cpn10 antibody, zgc:86747 antibody, hspe1 antibody, MGC89647 antibody, HSPE1 antibody, MITOCHONDRIAL CHAPERONIN 10 antibody, T15D22.2 antibody, T15D22_2 antibody, chaperonin 10 antibody, Dmel\\CG11267 antibody, Hsp10 antibody, anon-WO0118547.175 antibody, hsp10 antibody, crpB antibody, chpS antibody, 10kDa antibody, mt-cpn10 antibody, heat shock protein family E (Hsp10) member 1 antibody, molecular chaperone GroES antibody, chaperonin 10 kDa antibody, chaperonin, 10 kDa antibody, chaperonin-10 kDa antibody, heat shock protein family E member 1 antibody, heat shock 10 protein 1 antibody, heat shock protein family E (Hsp10) member 1 L homeolog antibody, heat shock 10kDa protein 1 (chaperonin 10) pseudogene antibody, 10 kd chaperonin antibody, chaperonin 10 antibody, Hsp10p antibody, co-chaperonin 10, mitochondrial antibody, CG11267 gene product from transcript CG11267-RA antibody, co-chaperonin GroES antibody, mitochondrial heat shock protein Hsp10 (predicted) antibody, chaperonin GroS antibody, Hsp10 10 kDa chaperonin GROES antibody, mitochondrial heat shock protein Hsp10 antibody, heat shock protein 10 antibody, heat shock protein 1 (chaperonin 10) antibody, heat shock 10kDa protein 1 (chaperonin 10) antibody, HSPE1 antibody, groES antibody, groES2 antibody, TP01_0190 antibody, Cag_1167 antibody, Bm1_56470 antibody, Hspe1 antibody, hspe1 antibody, hspe1.L antibody, LOC452179 antibody, Cpn10 antibody, CPN10 antibody, HSP10 antibody, CG11267 antibody, hsp10 antibody, groS antibody
    背景

    Description: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:7912672, PubMed:1346131, PubMed:11422376). The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).

    Gene: HSPE1

    分子量
    10kDa
    基因ID
    3336
    UniProt
    P61604
    途径
    Positive Regulation of Endopeptidase Activity
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