H2AFY 抗体 (AA 180-301) (Fluoro550)
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Quick Overview for H2AFY 抗体 (AA 180-301) (Fluoro550) (ABIN7995936)
抗原
See all H2AFY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-301
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原理
- Anti-H2AFY/MACROH2A1 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse,rat MACROH2A1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human H2AFY/MACROH2A1 recombinant protein (Position: A180-K301). Human MACROH2A1 shares 97.5% amino acid (aa) sequence identity with both mouse and rat MACROH2A1.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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别名
- MACROH2A1
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背景
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Background: Core histone macro-H2A.1 is a protein that in humans is encoded by the H2AFY gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: macroH2A.1 histone
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基因ID
- 9555
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UniProt
- O75367
抗原
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