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H2AFX 抗体 (AA 2-121) (Fluoro647)

The 兔 多克隆 anti-H2AFX antibody is suitable to detect H2AFX in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7995931
发货至: 中国
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for H2AFX 抗体 (AA 2-121) (Fluoro647) (ABIN7995931)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 86
多克隆

标记

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This H2AFX antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 2-121

    原理

    Anti-Histone H2A.X/H2AFX Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Histone H2A.X/H2AFX recombinant protein (Position: S2-T121).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    H2AFX

    背景

    Background: H2A histone family member X (usually abbreviated asH2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

    Gene Full Name: H2A.X variant histone

    基因ID

    3014

    UniProt

    P16104

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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