GRB10 抗体 (AA 1-251) (HRP)
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Quick Overview for GRB10 抗体 (AA 1-251) (HRP) (ABIN7995378)
抗原
See all GRB10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-251
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原理
- Anti-GRB10 Antibody (monoclonal, 5H7) HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRB10 recombinant protein (Position: M1-K251).
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亚型
- IgG1
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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别名
- GRB10
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背景
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Background: GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors (e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Full Name: growth factor receptor bound protein 10
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基因ID
- 2887
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UniProt
- Q13322
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途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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