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GSTA1 抗体 (N-Term) (APC)

The 兔 多克隆 anti-GSTA1 antibody is suitable to detect GSTA1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7994224
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GSTA1 抗体 (N-Term) (APC) (ABIN7994224)

抗原

See all GSTA1 抗体
GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

适用

  • 95
  • 55
  • 40
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 98
  • 25

克隆类型

  • 99
  • 24
多克隆

标记

  • 48
  • 16
  • 16
  • 7
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GSTA1 antibody is conjugated to APC

应用范围

  • 71
  • 39
  • 34
  • 31
  • 19
  • 18
  • 13
  • 5
  • 5
  • 4
  • 4
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 38
    • 15
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    N-Term

    原理

    Anti-GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human GSTA1/A2/A3/A4/A5, different from the related mouse and rat sequences by five amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

    别名

    GSTA1

    背景

    Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules). In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity, thereby protecting the cells from reactive oxygen species and the products of peroxidation.

    Gene Full Name: glutathione S-transferase alpha 1

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    基因ID

    2938, 2939, 2940

    UniProt

    P08263
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