GPX4 抗体 (AA 30-197) (HRP)
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北京 101111
Quick Overview for GPX4 抗体 (AA 30-197) (HRP) (ABIN7994201)
抗原
See all GPX4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 30-197
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原理
- Anti-Glutathione Peroxidase 4/GPX4 Antibody (monoclonal, 6I4E7) HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Glutathione Peroxidase 4/GPX4 recombinant protein (Position: A30-F197).
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亚型
- IgG2b
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- GPX4 (Glutathione Peroxidase 4 (GPX4))
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别名
- GPX4
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背景
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Background: Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. This gene encodes a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants.
Gene Full Name: glutathione peroxidase 4
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基因ID
- 2879
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UniProt
- P36969
抗原
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