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GCLC 抗体 (AA 24-388) (Fluoro647)

The 兔 多克隆 anti-GCLC antibody is suitable to detect GCLC in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7993939
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GCLC 抗体 (AA 24-388) (Fluoro647) (ABIN7993939)

抗原

See all GCLC 抗体
GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

适用

  • 86
  • 46
  • 43
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
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  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 4

克隆类型

  • 76
  • 15
多克隆

标记

  • 46
  • 6
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  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
This GCLC antibody is conjugated to Fluoro647

应用范围

  • 58
  • 34
  • 32
  • 31
  • 16
  • 11
  • 9
  • 8
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 12
    • 9
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    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
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    AA 24-388

    原理

    Anti-GCLC Antibody Fluoro647 Conjugated

    预测反应

    Human GCLC shares 94.2%,93.7% amino acid (aa) sequence identity with mouse,rat GCLC,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GCLC recombinant protein (Position: R24-H388). Human GCLC shares 94.2% and 93.7% amino acid (aa) sequence identity with mouse and rat GCLC, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

    别名

    GCLC

    背景

    Background: GCLC, Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6p12.1. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.

    Gene Full Name: glutamate-cysteine ligase catalytic subunit

    基因ID

    2729

    UniProt

    P48506

    途径

    Cell RedoxHomeostasis
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