GCLC 抗体 (AA 437-637) (PE)
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Quick Overview for GCLC 抗体 (AA 437-637) (PE) (ABIN7993927)
抗原
See all GCLC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 437-637
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原理
- Anti-GCLC Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human GCLC shares 94% amino acid (aa) sequence identity with both mouse,rat GCLC.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GCLC recombinant protein (Position: E437-N637). Human GCLC shares 94% amino acid (aa) sequence identity with both mouse and rat GCLC.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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别名
- GCLC
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背景
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Background: GCLC, also named Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6p12.1. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
Gene Full Name: glutamate-cysteine ligase catalytic subunit
Sequence Similarities: Belongs to the glutamate--cysteine ligase type 3 family.
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基因ID
- 2729
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UniProt
- P48506
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途径
- Cell RedoxHomeostasis
抗原
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