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GRID2 抗体 (N-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-GRID2 antibody (ABIN7993742) specifically detects GRID2 in WB, ELISA 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7993742
发货至: 中国
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Quick Overview for GRID2 抗体 (N-Term) (Biotin) (ABIN7993742)

抗原

See all GRID2 抗体
GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

适用

  • 28
  • 26
  • 25
  • 2
人, 大鼠, 小鼠

宿主

  • 27
  • 2

克隆类型

  • 28
  • 1
多克隆

标记

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRID2 antibody is conjugated to Biotin

应用范围

  • 14
  • 11
  • 8
  • 6
  • 6
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term

    原理

    Anti-GRID2 Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human GRID2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

    别名

    GRID2

    背景

    Background: Glutamate receptor, ionotropic, delta 2, also known as GluD2, GluRδ2, or δ2, is a protein that in humans is encoded by the GRID2 gene. The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.

    Gene Full Name: glutamate ionotropic receptor delta type subunit 2

    基因ID

    2895

    UniProt

    O43424

    途径

    Synaptic Membrane
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