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Glutamate Receptor 1 抗体 (AA 19-360) (Biotin)

The 兔 多克隆 anti-Glutamate Receptor 1 antibody is suitable to detect Glutamate Receptor 1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7993675
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Glutamate Receptor 1 抗体 (AA 19-360) (Biotin) (ABIN7993675)

抗原

See all Glutamate Receptor 1 (GLUR1) 抗体
Glutamate Receptor 1 (GLUR1)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Glutamate Receptor 1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 19-360

    原理

    Anti-Glutamate Receptor 1/GRIA1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse,rat GRIA1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Glutamate Receptor 1 (GLUR1)

    别名

    GRIA1

    背景

    Background: GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

    Gene Full Name: glutamate ionotropic receptor AMPA type subunit 1

    基因ID

    2890

    UniProt

    P42261

    途径

    PI3K-Akt Signaling
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