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GPI 抗体 (N-Term) (PE)

The PE-conjugated 兔 多克隆 anti-GPI antibody (ABIN7993496) specifically detects GPI in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7993496
发货至: 中国
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Quick Overview for GPI 抗体 (N-Term) (PE) (ABIN7993496)

抗原

See all GPI 抗体
GPI (Glucose-6-Phosphate Isomerase (GPI))

适用

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小鼠

宿主

  • 131
  • 34
  • 1

克隆类型

  • 112
  • 54
多克隆

标记

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This GPI antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-Glucose 6 phosphate isomerase/GPI Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related human sequence by sixteen amino acids,and from the related rat sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of mouse GPI, different from the related human sequence by sixteen amino acids, and from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GPI (Glucose-6-Phosphate Isomerase (GPI))

    别名

    Gpi

    背景

    Background: Glucose-6-phosphate isomerase (GPI), alternatively known as phosphoglucose isomerase (PGI) or phosphohexose isomerase (PHI), is an enzyme that in humans is encoded by the GPI gene on chromosome 19. This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.

    Gene Full Name: glucose-6-phosphate isomerase 1

    基因ID

    14751

    UniProt

    P06745
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