GCK 抗体 (AA 234-431)
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北京 101111
Quick Overview for GCK 抗体 (AA 234-431) (ABIN7993410)
抗原
See all GCK 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 234-431
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原理
- Anti-Glucokinase/GCK Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Glucokinase/GCK Antibody. Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Glucokinase recombinant protein (Position: Y234-T431).
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亚型
- IgG
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anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 101-200) antibodyGCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 3-226) antibodyGCK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 403-433), (C-Term) antibodyGCK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB05339 unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-300) antibodyGCK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5845 unconjugated Recombinant Antibody
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- GCK (Glucokinase (Hexokinase 4) (GCK))
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别名
- GCK
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背景
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Background: Glucokinase (GCK) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Gene Full Name: glucokinase
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分子量
- 52 kDa
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基因ID
- 2645
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UniProt
- P35557
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途径
- MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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