GLI2 抗体 (AA 46-1398)
Our Local Distributor
北京 101111
Quick Overview for GLI2 抗体 (AA 46-1398) (ABIN7993245)
抗原
See all GLI2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 46-1398
-
原理
- Anti-GLI2 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-GLI2 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GLI2 recombinant protein (Position: A46-A1398).
-
亚型
- IgG
-
-
anti-GLI Family Zinc Finger 2 (GLI2) (Middle Region) antibody
GLI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 1287-1321), (C-Term) antibodyGLI2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB49147 unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 721-1457) antibodyGLI2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 600-649) antibodyGLI2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 1287-1321), (C-Term) antibodyGLI2 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (N-Term) antibodyGLI2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 2-20) antibodyGLI2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (AA 30-65) antibodyGLI2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLI Family Zinc Finger 2 (GLI2) (Internal Region) antibodyGLI2 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- GLI2 (GLI Family Zinc Finger 2 (GLI2))
-
别名
- GLI2
-
背景
-
Background: GLI2 (Gli-Kruppel Family Member 2), also called ONCOGENE GLI2, is a protein that in humans is encoded by the GLI2 gene. Sequencing of GLI cDNA clones showed the presence of 5 tandem zinc fingers connected by histidine-cysteine links, which indicated that the gene belongs to the family of zinc finger genes related to Kruppel (Kr). The Drosophila gene Kr is a member of the gap class of segmentation genes, thoracic and anterior abdominal segments fail to form in Kr mutant embryos. By fluorescence in situ hybridization, Matsumoto et al. (1996) refined the assignment of the GLI2 gene to chromosome 2q14. Roessler et al. (2005) showed that GLI2-delta-N exhibited potent transcriptional activity in vivo: overexpression in mouse skin led to the formation of hedgehog-independent epithelial downgrowths resembling basal cell carcinomas, which in humans are associated with constitutive hedgehog signaling.
Gene Full Name: GLI family zinc finger 2
-
分子量
- 180-200 kDa
-
基因ID
- 2736
-
UniProt
- P10070
-
途径
- Hedgehog Signaling, Dopaminergic Neurogenesis
抗原
-
