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GLI2 抗体 (AA 46-1398) (PE)

The 兔 多克隆 anti-GLI2 antibody is suitable to detect GLI2 in samples from 人 和 大鼠. It has been validated for FACS.
产品编号 ABIN7993243
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GLI2 抗体 (AA 46-1398) (PE) (ABIN7993243)

抗原

See all GLI2 抗体
GLI2 (GLI Family Zinc Finger 2 (GLI2))

适用

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  • 1
人, 大鼠

宿主

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克隆类型

  • 61
  • 2
多克隆

标记

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This GLI2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 46-1398

    原理

    Anti-GLI2 Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GLI2 recombinant protein (Position: A46-A1398).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GLI2 (GLI Family Zinc Finger 2 (GLI2))

    别名

    GLI2

    背景

    Background: GLI2 (Gli-Kruppel Family Member 2), also called ONCOGENE GLI2, is a protein that in humans is encoded by the GLI2 gene. Sequencing of GLI cDNA clones showed the presence of 5 tandem zinc fingers connected by histidine-cysteine links, which indicated that the gene belongs to the family of zinc finger genes related to Kruppel (Kr). The Drosophila gene Kr is a member of the gap class of segmentation genes, thoracic and anterior abdominal segments fail to form in Kr mutant embryos. By fluorescence in situ hybridization, Matsumoto et al. (1996) refined the assignment of the GLI2 gene to chromosome 2q14. Roessler et al. (2005) showed that GLI2-delta-N exhibited potent transcriptional activity in vivo: overexpression in mouse skin led to the formation of hedgehog-independent epithelial downgrowths resembling basal cell carcinomas, which in humans are associated with constitutive hedgehog signaling.

    Gene Full Name: GLI family zinc finger 2

    基因ID

    2736

    UniProt

    P10070

    途径

    Hedgehog Signaling, Dopaminergic Neurogenesis
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