GIT1 抗体 (AA 415-736) (FITC)
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北京 101111
Quick Overview for GIT1 抗体 (AA 415-736) (FITC) (ABIN7993218)
抗原
See all GIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 415-736
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原理
- Anti-GIT1 Antibody FITC Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GIT1 recombinant protein (Position: D415-Q736).
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亚型
- IgG
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anti-GIT1 (GIT1) (AA 460-640) antibody
KO Validated GIT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-GIT1 (GIT1) (AA 415-736) antibodyGIT1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-GIT1 (GIT1) (AA 533-561), (C-Term), (Tyr554) antibodyGIT1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB15351 unconjugated
anti-GIT1 (GIT1) (AA 470-642) antibodyGIT1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GIT1 (GIT1) (Internal Region) antibodyGIT1 适用: 人, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-GIT1 (GIT1) (Internal Region) antibodyGIT1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GIT1 (GIT1) (AA 487-517) antibodyGIT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15373 unconjugated
anti-GIT1 (GIT1) (AA 375-770) antibody (Atto 390)GIT1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal S39B-8 Atto 390
anti-GIT1 (GIT1) (AA 375-770) antibody (Atto 488)GIT1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal S39B-8 Atto 488
anti-GIT1 (GIT1) (AA 375-770) antibody (Atto 594)GIT1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal S39B-8 Atto 594
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GIT1
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别名
- GIT1
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背景
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Background: ARF GTPase-activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT-1 and GIT-2) are highly conserved, ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics. GIT proteins contain multiple interaction domains that allow interaction with small GTPases (including ARF, Rac and cdc42), kinases (such as PAK and MEK), the Rho family GEF PIX, and the focal adhesion protein paxillin. GIT-1 is localized to focal adhesions, cytoplasmic complexes and membrane protrusions, and regulates cell protrusion formation and cell migration. GIT-1 has also been implicated in neuronal functions including synapse formation and the pathology of Huntington disease. Huntington disease is a genetic neurodegenerative condition involving a mutation in the huntington gene. The huntington gene product (htt) is ubiquitinated and degraded in human Huntington disease brains. Htt interacts ly with GIT-1 causing enhanced htt proteolysis, indicating that GIT-1 distribution and function may contribute to Huntington disease pathology.
Gene Full Name: GIT ArfGAP 1
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基因ID
- 28964
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UniProt
- Q9Y2X7
抗原
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