GFRA2 抗体 (AA 30-425)
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北京 101111
Quick Overview for GFRA2 抗体 (AA 30-425) (ABIN7993036)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 30-425
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原理
- Anti-GFRA2 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.
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产品特性
- Anti-GFRA2 Antibody. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunofluorescence, 5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRA2
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背景
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Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: GDNF family receptor alpha 2
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分子量
- 52 kDa
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基因ID
- 2675
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UniProt
- O00451
抗原
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