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GFRA2 抗体

GFRA2 适用: 人 WB, ELISA, IF 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN1450225
发货至: 中国
  • 抗原 See all GFRA2 抗体
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    适用
    • 51
    • 27
    • 24
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    宿主
    • 49
    • 1
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    小鸡
    克隆类型
    • 50
    • 1
    多克隆
    标记
    • 24
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    • 4
    • 2
    • 2
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    This GFRA2 antibody is un-conjugated
    应用范围
    • 48
    • 23
    • 13
    • 13
    • 6
    • 5
    • 4
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    • 2
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    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    特异性
    Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. GFRa-2 isa member of the GDNF receptor family. It is a glycosylphosphatidyl-inositol(GPI)-linkedcell surface receptor for both GDNF and NTN, and mediates activation of the RETtyrosine kinase receptor. This encoded protein acts preferentially as areceptor for NRTN compared to its other family member, GDNF family receptoralpha 1. http://www.ncbi.nlm.nih.gov/gene/2675
    产品特性
    Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.
    纯化方法
    GFRa-2 affinity purified
    亚型
    IgY
    Top Product
    Discover our top product GFRA2 Primary Antibody
  • 应用备注
    Western immunoblotting, recommended dilution 1:5 000to 1:10 000, ELISA: 1:128 000 to 160 000, IF 1:500 to1:1000. Polyclonal antibody working titer has to beestablished practically for each particular antigen and assay format
    说明

    Synonym: GDNF receptor beta, Neurturin receptor alpha, RETligand 2TGF-beta-related neurotrophic factor receptor 2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml
    缓冲液
    Concentrated ammonium sulphate in PBS pH 7.4
    注意事项
    As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
    储存条件
    4 °C
    储存方法
    This product is shipped in non-frozen liquid form in ambient conditions
  • Siatra, Vatsellas, Chatzianastasiou, Balafas, Manolakou, Papapetropoulos, Agapaki, Mouchtouri, Ruchaya, Korovesi, Mavroidis, Thanos, Beis, Kokkinopoulos: "Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart." in: NPJ Regenerative medicine, Vol. 8, Issue 1, pp. 13, (2023) (PubMed).

  • 抗原
    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
    别名
    GFRa-2 (GFRA2 产品)
    别名
    GDNFRB antibody, NRTNR-ALPHA antibody, NTNRA antibody, RETL2 antibody, TRNR2 antibody, Retl2 antibody, NTNRALPHA antibody, ntnra antibody, retl2 antibody, trnr2 antibody, gdnfrb antibody, nrtnr-alpha antibody, gfra2 antibody, GDNF family receptor alpha 2 antibody, glial cell line derived neurotrophic factor family receptor alpha 2 antibody, GDNF family receptor alpha 2a antibody, GFRA2 antibody, Gfra2 antibody, gfra2 antibody, gfra2a antibody
    背景
    Recombinant His-tagged human GFRα-2 protein producedusing CHO-based cell line. For production of hGFRα-2, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant
    UniProt
    O00451
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