GFRA2 抗体 (AA 30-425) (HRP)
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Quick Overview for GFRA2 抗体 (AA 30-425) (HRP) (ABIN7993032)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-425
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原理
- Anti-GFRA2 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRA2
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背景
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Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: GDNF family receptor alpha 2
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基因ID
- 2675
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UniProt
- O00451
抗原
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