GJB2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for GJB2 抗体 (N-Term) (ABIN7992738)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- N-Term
-
原理
- Anti-Gap junction beta-2 protein GJB2 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- different from the related mouse,rat sequences by one amino acid.
-
产品特性
- Anti-Gap junction beta-2 protein GJB2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GJB2, different from the related mouse and rat sequences by one amino acid.
-
亚型
- IgG
-
-
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (C-Term) antibody
Verified GJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 99-131) antibodyGJB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Cytoplasmic Domain) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal CX-12H10 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 1-226) antibodyGJB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Middle Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) antibodyGJB2 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (AA 85-134) antibodyGJB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (Internal Region) antibodyGJB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gap Junction Protein, beta 2, 26kDa (GJB2) (N-Term) antibodyGJB2 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
-
储存液
- Sodium azide, Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
-
别名
- GJB2
-
背景
-
Background: Connexin26 (CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5 % identity with rat Cx26. connexin 26 (GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene (GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.
Gene Full Name: gap junction protein beta 2
Sequence Similarities: Belongs to the connexin family. Beta-type (group I) subfamily.
-
分子量
- 82 kDa
-
基因ID
- 2706
-
UniProt
- P29033
-
途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
-
