FURIN 抗体 (AA 591-794) (APC)
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Quick Overview for FURIN 抗体 (AA 591-794) (APC) (ABIN7991996)
抗原
See all FURIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 591-794
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原理
- Anti-Furin Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Furin shares 88% amino acid (aa) sequence identity with both mouse,rat Furin.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Furin recombinant protein (Position: T591-L794). Human Furin shares 88% amino acid (aa) sequence identity with both mouse and rat Furin.
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亚型
- IgG
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anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 120-370) antibody
FURIN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 587-748) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 418-573) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (Internal Region) antibodyVerified FURIN 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyKD Validated FURIN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2160 unconjugated Recombinant Antibody
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 385-500) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 578-734) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 520-701) antibodyFURIN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1C3 unconjugated Recombinant Antibody
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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别名
- FURIN
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背景
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Background: Furin (Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.
Gene Full Name: furin, paired basic amino acid cleaving enzyme
Sequence Similarities: Belongs to the peptidase S8 family. Furin subfamily.
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基因ID
- 5045
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UniProt
- P09958
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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