FLT3 抗体 (AA 62-295)
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北京 101111
Quick Overview for FLT3 抗体 (AA 62-295) (ABIN7991193)
抗原
See all FLT3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 62-295
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原理
- Anti-Flt3/CD135 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Flt3/CD135 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse Flt3 / CD135 recombinant protein (Position: E62-E295).
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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别名
- Flt3
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背景
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Background: Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow.
Gene Full Name: FMS-like tyrosine kinase 3
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分子量
- 150 kDa
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基因ID
- 14255
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UniProt
- Q00342
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途径
- RTK signaling
抗原
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