FKBP15 抗体 (AA 19-1210) (Fluoro550)
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北京 101111
Quick Overview for FKBP15 抗体 (AA 19-1210) (Fluoro550) (ABIN7990955)
抗原
See all FKBP15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-1210
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原理
- Anti-FKBP135/FKBP15 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FKBP135/FKBP15 recombinant protein (Position: A19-D1210).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))
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别名
- FKBP15
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背景
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Background: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.
Gene Full Name: FKBP prolyl isomerase family member 15
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基因ID
- 23307
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UniProt
- Q5T1M5
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途径
- SARS-CoV-2 Protein Interactome
抗原
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