FGF8 抗体 (C-Term) (HRP)
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Quick Overview for FGF8 抗体 (C-Term) (HRP) (ABIN7990681)
抗原
See all FGF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Fibroblast growth factor 8 FGF8 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human FGF8, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibody
FGF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 131-233) antibodyFGF8 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 30-59), (N-Term) antibodyFGF8 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40263 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 32-66), (N-Term) antibodyFGF8 适用: 人 WB 宿主: 兔 Polyclonal RB49207 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyVerified FGF8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyFGF8 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 23-143) antibodyFGF8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) antibodyFGF8 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 斑马鱼, Pig, Bat, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
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别名
- FGF8
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背景
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Background: Fibroblast growth factor 8 (androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene are secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patterning of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast, it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus. FGF8 in adults expression is restricted to the gonads. We detected rat ovary in our lab.
Gene Full Name: fibroblast growth factor 8
Sequence Similarities: Belongs to the heparin-binding growth factors family.
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基因ID
- 2253
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UniProt
- P55075
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
抗原
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