FERMT2 抗体 (AA 1-650) (PE)
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Quick Overview for FERMT2 抗体 (AA 1-650) (PE) (ABIN7990265)
抗原
See all FERMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-650
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原理
- Anti-Kindlin 2/FERMT2 Antibody PE Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Kindlin 2/FERMT2 recombinant protein (Position: M1-I650).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- FERMT2 (Fermitin Family Member 2 (FERMT2))
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别名
- FERMT2
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背景
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Background: Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene. Enables several functions, including actin binding activity, phosphatidylinositol-3,4,5-trisphosphate binding activity, and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell differentiation, and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol, focal adhesion, and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia.
Gene Full Name: FERM domain containing kindlin 2
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基因ID
- 10979
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UniProt
- Q96AC1
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途径
- Cell-Cell Junction Organization
抗原
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