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FER 抗体 (AA 1-804) (PE)

The PE-conjugated 兔 多克隆 anti-FER antibody (ABIN7990232) specifically detects FER in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7990232
发货至: 中国
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Room 801-803
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Quick Overview for FER 抗体 (AA 1-804) (PE) (ABIN7990232)

抗原

See all FER 抗体
FER (FER Tyrosine Kinase (FER))

适用

  • 100
  • 77
  • 41
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 112
  • 13

克隆类型

  • 111
  • 14
多克隆

标记

  • 58
  • 6
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This FER antibody is conjugated to PE

应用范围

  • 95
  • 41
  • 26
  • 26
  • 25
  • 21
  • 17
  • 13
  • 6
  • 5
  • 4
  • 2
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 27
    • 15
    • 12
    • 12
    • 11
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-804

    原理

    Anti-FER Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FER recombinant protein (Position: M1-R804).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FER (FER Tyrosine Kinase (FER))

    别名

    FER

    背景

    Background: FER(FPS/FES-Related tyrosine kinase) also known as TYK3, is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. By in situ hybridization, Morris et al.(1990) concluded that the FER gene is located at 5q21-q22. Treatment of cells with JMP resulted in the release of FER from the cadherin complex and its accumulation in the integrin complex. The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER. The results suggested that FER mediates crosstalk between CDH2 and ITGB1. In Fer mutant mice, leukocyte emigration was exaggerated in response to LPS without altering vascular permeability, suggesting that FER has a role in regulating innate immunity.

    Gene Full Name: FER tyrosine kinase

    基因ID

    2241

    UniProt

    P16591
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