FER 抗体 (pTyr402)
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北京 101111
Quick Overview for FER 抗体 (pTyr402) (ABIN6255906)
抗原
See all FER 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr402
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特异性
- Phospho-FER (Tyr402) Antibody detects endogenous levels of FER only when phosphorylated at Tyrosine 402.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human FER around the phosphorylation site of Tyr402.
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亚型
- IgG
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anti-FER Tyrosine Kinase (FER) (AA 782-811), (C-Term) antibody
FER 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB03222 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5D2C4 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 1-300) antibodyFER 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 1457CT181-12-17 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1487CT794-8-50 unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (Ser376) antibodyFER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (AA 521-536), (Middle Region) antibodyFER 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 犬, Cow, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人 WB, IP, DB 宿主: 小鼠 Monoclonal 2358C3a unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FER (FER Tyrosine Kinase (FER))
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别名
- FER
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背景
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Description: Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.
Gene: FER
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分子量
- 85kDa
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基因ID
- 2241
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UniProt
- P16591
抗原
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