Keratin 10 抗体 (AA 151-250) (FITC)
Quick Overview for Keratin 10 抗体 (AA 151-250) (FITC) (ABIN749340)
抗原
See all Keratin 10 (KRT10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-250
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特异性
- This antibody my have secondary cross-reactivities with Keratin 12, 13, 14, 15, 17 based on an 85 % sequence similarity in the immunogen range.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CK10
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亚型
- IgG
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anti-Keratin 10 (KRT10) (AA 153-456) antibody
KRT10 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RKSE60 unconjugated
anti-Keratin 10 (KRT10) (AA 345-454) antibodyKRT10 适用: 人, 小鼠, 大鼠, 猴 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 3C2F5 unconjugated
anti-Keratin 10 (KRT10) (AA 1-584) antibodyKRT10 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠, 犬, Pig IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RKSE60 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1D8 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人, 小鼠 IHC, WB, StM 宿主: 小鼠 Monoclonal LH2 unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人 IHC (p), ICC, IP 宿主: 小鼠 Monoclonal VIK-10 unconjugated
anti-Keratin 10 (KRT10) (Internal Region) antibodyKRT10 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 10 (KRT10) antibodyKRT10 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-610M unconjugated Recombinant Antibody
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Keratin 10 (KRT10)
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别名
- Cytokeratin 10
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背景
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Synonyms: BIE, EHK, K10, KPP, BCIE, CK10, Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, KRT10
Background: Cytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.
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基因ID
- 3858
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UniProt
- P13645
抗原
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