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EWSR1 抗体 (Middle Region) (Fluoro594)

The 小鼠 单克隆 anti-EWSR1 antibody is suitable to detect EWSR1 in samples from 人, 小鼠 和 猴. It has been validated for FACS.
产品编号 ABIN7989214
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EWSR1 抗体 (Middle Region) (Fluoro594) (ABIN7989214)

抗原

See all EWSR1 抗体
EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

适用

  • 115
  • 76
  • 60
  • 16
  • 11
  • 8
  • 8
  • 7
  • 7
  • 7
  • 5
  • 3
  • 2
  • 1
人, 小鼠, 猴

宿主

  • 92
  • 20
  • 3
  • 1
小鼠

克隆类型

  • 74
  • 42
单克隆

标记

  • 61
  • 8
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This EWSR1 antibody is conjugated to Fluoro594

应用范围

  • 91
  • 33
  • 31
  • 26
  • 22
  • 17
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

4B4
  • 抗原表位

    • 25
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-EWSR1 Antibody (monoclonal, 4B4) Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human EWSR1, different from the related mouse sequence by one amino acid.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

    别名

    EWSR1

    背景

    Background: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t (11,22) (q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

    Gene Full Name: EWS RNA binding protein 1

    基因ID

    2130

    UniProt

    Q01844
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