EGLN1 抗体 (C-Term)
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北京 101111
Quick Overview for EGLN1 抗体 (C-Term) (ABIN7987210)
抗原
See all EGLN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-PHD2/EGLN1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human PHD2,EGLN1 shares 100% amino acid (aa) sequence identity with both mouse,rat PHD2,EGLN1.
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产品特性
- Anti-PHD2/EGLN1 Antibody. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PHD2/EGLN1. Human PHD2/EGLN1 shares 100% amino acid (aa) sequence identity with both mouse and rat PHD2/EGLN1.
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亚型
- IgG
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anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-426) antibody
KO Validated EGLN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 42-140) antibodyEGLN1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 272-355) antibodyEGLN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (Internal Region) antibodyEGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (C-Term) antibodyEGLN1 适用: 人, 小鼠, 大鼠, 兔, 犬, 猴, Cow, 豚鼠, 马, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-24) antibodyEGLN1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 366G-76-3 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 396-425), (C-Term) antibodyEGLN1 适用: 人 WB 宿主: 兔 Polyclonal RB39542 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 1-50) antibodyEGLN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1) (AA 301-426) antibodyEGLN1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
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别名
- EGLN1
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背景
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Background: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).
Gene Full Name: egl-9 family hypoxia inducible factor 1
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分子量
- 46 kDa
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基因ID
- 54583
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UniProt
- Q9GZT9
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途径
- cAMP Metabolic Process, Warburg Effect
抗原
-
