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ECD/SGT1 抗体 (AA 50-567) (Fluoro647)

This 兔 多克隆 antibody specifically detects ECD/SGT1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7987098
发货至: 中国
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Quick Overview for ECD/SGT1 抗体 (AA 50-567) (Fluoro647) (ABIN7987098)

抗原

See all ECD/SGT1 (ECD) 抗体
ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

适用

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宿主

  • 46
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克隆类型

  • 47
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多克隆

标记

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This ECD/SGT1 antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 50-567

    原理

    Anti-SGT1/ECD Antibody Fluoro647 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SGT1/ECD recombinant protein (Position: L50-Q567).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))

    别名

    ECD

    背景

    Background: Protein SGT1 is a protein that in humans is encoded by the ECD gene. Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.

    Gene Full Name: ecdysoneless cell cycle regulator

    基因ID

    11319

    UniProt

    O95905

    途径

    Regulation of Carbohydrate Metabolic Process
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